Machete Labz
(quantity of products: 11)Machete Labz is a brand with a clearly defined profile — the portfolio focuses on research compounds described in the scientific literature: SARMs (Ligandrol, Ostarine, Testolone), a PPARδ receptor agonist (Cardarine), growth hormone secretagogues (Ibutamoren MK-677, Acetamoren MK-777), and adrenergic ingredients (Alpha Yohimbine). The lineup is rounded out with plant-based formulas such as Don Juan. The products are available mainly in capsules, in several package variants, and the brand describes them with precise compound designations.
What characterizes Machete Labz
The brand has a clearly defined profile. Instead of a broad catalog of classic supplements, Machete Labz focuses on a narrow, coherent group of compounds described in the scientific literature — the kind that have been the subject of research discussion for years.
Three features distinguish the portfolio:
- Capsule form — a convenient, consistent format, usually available in two package sizes (e.g., 30 and 60 capsules), which lets you match the variant to your own needs.
- Precise naming — the brand describes its products with specific compound designations (LGD-4033, MK-2866, RAD-140, GW-501516, MK-677), not vague trade names. With compounds that have similar symbols, this has practical significance.
- Rounded out with plant-based formulas — alongside the research compounds, the brand also offers a classic dietary supplement based on plant extracts.
The Machete Labz portfolio
Selective androgen receptor modulators (SARMs)
The largest group in the lineup — nonsteroidal research compounds that act on the androgen receptor with tissue selectivity:
- Machete Labz Ligandrol — contains LGD-4033 (ligandrol), one of the more clinically studied compounds in this class.
- Machete Labz Ostarine — contains ostarine (MK-2866 / enobosarm), the most clinically documented SARM.
- Machete Labz Testolone — contains RAD-140 (testolone), a compound developed by Radius Health, with a high affinity for the androgen receptor.
PPARδ receptor agonist
- Machete Labz Cardarine — contains GW-501516 (cardarine). It's worth knowing that cardarine is sometimes incorrectly counted among the SARMs, though it belongs to a distinct class — the PPARδ receptor agonists.
Growth hormone secretagogues
Compounds that act on the growth hormone secretion pathway through ghrelin receptor agonism:
- Machete Labz Ibutamoren MK-677 — contains MK-677 (ibutamoren), an established secretagogue widely described in the literature.
- Machete Labz Acetamoren — contains a compound designated as MK-777 (acetamoren). This is a trade name for a form linked to ibutamoren, with a considerably narrower body of independent data — it's worth distinguishing it from the established MK-677.
Adrenergic ingredients
- Machete Labz Alpha Yohimbine — contains alpha-yohimbine (rauwolscine), an indole alkaloid that is a stereoisomer of yohimbine, with an adrenergic profile (alpha-2 receptor antagonism).
Plant-based formulas
- Machete Labz Don Juan — a dietary supplement built on a blend of plant extracts traditionally found in formulas for men (Tongkat Ali, Maca, ashwagandha KSM-66®, Shilajit, Muira Puama, and others). Unlike the brand's other items, this is a classic dietary supplement.
The nature of the lineup — what's worth knowing
The core of the Machete Labz portfolio consists of compounds that are not registered as drugs or as dietary supplements and are not subject to EFSA health claims. Their legal status varies from country to country, and most of them (SARMs, growth hormone secretagogues, PPARδ agonists) appear on the WADA Prohibited List of Substances and Methods — so they are not permitted in sport subject to anti-doping control. The lineup is addressed to adults (21+).
The exception is the plant-based formulas, such as Don Juan — these are dietary supplements subject to the rules proper to that category.
The individual Machete Labz product cards contain a detailed profile of each compound: mechanism of action, study data, safety profile, and regulatory status.
Frequently asked questions about the Machete Labz brand
What is Machete Labz?
It is a brand in the HL Supps lineup whose portfolio mainly comprises research compounds (SARMs, growth hormone secretagogues, a PPARδ agonist, adrenergic ingredients) and plant-based formulas — available primarily in capsules.
What products does Machete Labz offer?
Among others: Ligandrol (LGD-4033), Ostarine (MK-2866), Testolone (RAD-140), Cardarine (GW-501516), Ibutamoren (MK-677), Acetamoren (MK-777), Alpha Yohimbine (rauwolscine), and an herbal dietary supplement for men — Don Juan.
What form do Machete Labz products come in?
Primarily capsules, usually in two package variants (e.g., 30 and 60 capsules).
Are Machete Labz products dietary supplements?
It depends on the product. A significant part of the lineup consists of research compounds, which are not dietary supplements or drugs. The exception is the plant-based formulas, such as Don Juan.
Editorial note
Compiled and pharmacologically reviewed by: Allisa Connor, PhD — Pharmacological Reviewer, HL Supps. Pharmacologist; the brand description was prepared on the basis of the profiles of the individual products, retaining the information about the research nature of a significant part of the portfolio and about the regulatory status of the ingredients.
Published: 2026-07-13 · Last updated: 2026-07-13
Informational material about the brand. This is not medical advice or an inducement to use any substance.